| 1. Round | 06/08/2022 | SC Cambuur | - | SBV Excelsior | 0:2 | ||||
| 2. Round | 13/08/2022 | FC Utrecht | - | SC Cambuur | 0:0 | ||||
| 3. Round | 20/08/2022 | Fortuna Sittard | - | SC Cambuur | 1:4 | ||||
| 4. Round | 28/08/2022 | SC Cambuur | - | AZ Alkmaar | 0:1 | ||||
| 5. Round | 03/09/2022 | AFC Ajax | - | SC Cambuur | 4:0 | ||||
| 6. Round | 11/09/2022 | SC Cambuur | - | FC Groningen | 0:1 | ||||
| 7. Round | 17/09/2022 | RKC Waalwijk | - | SC Cambuur | 5:1 | ||||
| 8. Round | 01/10/2022 | SC Cambuur | - | PSV Eindhoven | 3:0 | ||||
| 9. Round | 09/10/2022 | Go Ahead Eagles | - | SC Cambuur | 0:0 | ||||
| 10. Round | 15/10/2022 | SC Cambuur | - | Vitesse | 0:3 | ||||
| 11. Round | 23/10/2022 | SC Cambuur | - | FC Twente | 0:1 | ||||
| 13. Round | 04/11/2022 | SC Cambuur | - | NEC Nijmegen | 0:1 | ||||
| 12. Round | 10/11/2022 | Feyenoord | - | SC Cambuur | 1:0 | ||||
| 14. Round | 13/11/2022 | sc Heerenveen | - | SC Cambuur | 2:1 | ||||
| 18. Round | 26/01/2023 | FC Groningen | - | SC Cambuur | 0:1 | ||||
| 19. Round | 29/01/2023 | SC Cambuur | - | Fortuna Sittard | 1:2 | ||||
| 33. Round | 21/05/2023 | Sparta Rotterdam | - | SC Cambuur | 4:1 | ||||
| 34. Round | 28/05/2023 | SC Cambuur | - | RKC Waalwijk | 4:0 |  |
France