| Round of 16 | 18/08/2022 | O'Higgins | - | Unión Española | 1:3 | ||||
| Round of 16 | 22/08/2022 | Unión Española | - | O'Higgins | 1:0 | ||||
| Quarter-finals | 24/09/2022 | Antofagasta | - | Unión Española | 1:2 | ||||
| Quarter-finals | 27/09/2022 | Unión Española | - | Antofagasta | 4:1 |  |
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| Semi-finals | 26/10/2022 | Universidad de Chile | - | Unión Española | 0:0 | ||||
| Semi-finals | 02/11/2022 | Unión Española | - | Universidad de Chile | 1:0 | ||||
| Final | 13/11/2022 | CD Magallanes | - | Unión Española | 7:6 pso | |
Chile