| 3. Round | 18/03/2023 | Guayaquil City | - | Mushuc Runa | 4:1 | ||||
| 4. Round | 01/04/2023 | Barcelona | - | Mushuc Runa | 1:0 | ||||
| 5. Round | 09/04/2023 | Mushuc Runa | - | Libertad de Loja | 2:1 |  |
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| 6. Round | 16/04/2023 | Delfín SC | - | Mushuc Runa | 3:0 | ||||
| 7. Round | 24/04/2023 | Mushuc Runa | - | Emelec | 0:0 | ||||
| 8. Round | 30/04/2023 | Cumbayá | - | Mushuc Runa | 1:1 | ||||
| 9. Round | 07/05/2023 | Mushuc Runa | - | El Nacional | 0:1 | ||||
| 10. Round | 13/05/2023 | Deportivo Cuenca | - | Mushuc Runa | 3:0 | ||||
| 13. Round | 03/06/2023 | Mushuc Runa | - | Orense SC | 3:1 |  |
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| 14. Round | 10/06/2023 | Universidad Catolica | - | Mushuc Runa | 3:2 | |
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| 15. Round | 18/06/2023 | Mushuc Runa | - | LDU Quito | 2:2 |
Argentina