| 1. Round | 06/02/2016 | San Martín de San Juan | - | Newell's Old Boys | 2:1 |  |
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| 2. Round | 14/02/2016 | Racing Club | - | San Martín de San Juan | 2:2 | ||||
| 3. Round | 18/02/2016 | San Martín de San Juan | - | Boca Juniors | 0:1 | ||||
| 4. Round | 23/02/2016 | Unión de Santa Fe | - | San Martín de San Juan | 1:1 | |
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| 5. Round | 29/02/2016 | San Martín de San Juan | - | Lanús | 2:2 | |
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| 6. Round | 05/03/2016 | Atlético Rafaela | - | San Martín de San Juan | 1:2 | |
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| 7. Round | 12/03/2016 | San Martín de San Juan | - | Tigre | 1:0 | ||||
| 8. Round | 18/03/2016 | Aldosivi | - | San Martín de San Juan | 2:2 | |
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| 9. Round | 03/04/2016 | San Martín de San Juan | - | Argentinos Juniors | 2:0 | ||||
| 10. Round | 09/04/2016 | Huracán | - | San Martín de San Juan | 4:3 | ||||
| 11. Round | 17/04/2016 | San Martín de San Juan | - | Estudiantes | 0:2 | |
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| 12. Round | 23/04/2016 | Godoy Cruz | - | San Martín de San Juan | 1:0 | |
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| 13. Round | 30/04/2016 | Defensa y Justicia | - | San Martín de San Juan | 0:0 | ||||
| 14. Round | 07/05/2016 | San Martín de San Juan | - | Temperley | 2:0 | |
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| 15. Round | 14/05/2016 | Atlético Tucumán | - | San Martín de San Juan | 3:2 | ||||
| 16. Round | 22/05/2016 | San Martín de San Juan | - | Godoy Cruz | 2:0 |
Argentina