| 1. Round | 13/08/2015 | Defensor Sporting | - | Bolívar | 3:0 | ||||
| 1. Round | 18/08/2015 | Bolívar | - | Defensor Sporting | 2:0 | ||||
| 2. Round | 26/08/2015 | Defensor Sporting | - | Universitario de Deportes | 3:0 | ||||
| 2. Round | 16/09/2015 | Universitario de Deportes | - | Defensor Sporting | 0:1 | ||||
| Round of 16 | 25/09/2015 | Lanús | - | Defensor Sporting | 0:0 |  |
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| Round of 16 | 02/10/2015 | Defensor Sporting | - | Lanús | 5:3 pso | |
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| Quarter-finals | 21/10/2015 | Huracán | - | Defensor Sporting | 1:0 | ||||
| Quarter-finals | 27/10/2015 | Defensor Sporting | - | Huracán | 0:0 |
Uruguay