1. Round | 10/02/2022 | Newell's Old Boys II | - | Defensa y Justicia II | 2:0 | ||||
2. Round | 15/02/2022 | Defensa y Justicia II | - | Racing Club II | 1:0 | ||||
3. Round | 21/02/2022 | San Lorenzo II | - | Defensa y Justicia II | 0:4 | ||||
4. Round | 26/02/2022 | Defensa y Justicia II | - | Gimnasia de La Plata II | 2:1 | ||||
11. Round | 20/04/2022 | Sarmiento de Junín II | - | Defensa y Justicia II | 0:1 | ||||
12. Round | 25/04/2022 | Defensa y Justicia II | - | Platense II | 1:1 | ||||
13. Round | 29/04/2022 | Unión de Santa Fe II | - | Defensa y Justicia II | 2:0 | ||||
14. Round | 06/05/2022 | Defensa y Justicia II | - | Patronato de Paraná II | 3:0 |