| 17. Round | 18/10/2021 | Unión de Santa Fe II | - | Racing Club II | 1:1 | ||||
| 18. Round | 24/10/2021 | Rosario Central II | - | Racing Club II | 1:2 | ||||
| 19. Round | 28/10/2021 | Racing Club II | - | Defensa y Justicia II | 2:2 | ||||
| 21. Round | 17/11/2021 | Racing Club II | - | Colón de Santa Fe II | 1:1 | ||||
| 22. Round | 23/11/2021 | River Plate II | - | Racing Club II | 1:2 | ||||
| 23. Round | 27/11/2021 | Racing Club II | - | Lanús II | 1:1 | ||||
| 24. Round | 02/12/2021 | Huracán II | - | Racing Club II | 0:3 |
Argentina