| 1. Round | 13/02/2021 | Vélez Sarsfield | - | Newell's Old Boys | 1:0 | ||||
| 5. Round | 13/03/2021 | Defensa y Justicia | - | Newell's Old Boys | 4:0 | ||||
| 10. Round | 18/04/2021 | Newell's Old Boys | - | Patronato de Paraná | 2:0 | ||||
| 11. Round | 26/04/2021 | Gimnasia de La Plata | - | Newell's Old Boys | 2:1 | ||||
| 12. Round | 03/05/2021 | Rosario Central | - | Newell's Old Boys | 3:0 |
Argentina