| 1. Round | 07/06/2022 | Argentinos Juniors | - | Aldosivi | 2:1 | ||||
| 2. Round | 11/06/2022 | Sarmiento de Junín | - | Argentinos Juniors | 1:0 | ||||
| 3. Round | 16/06/2022 | Argentinos Juniors | - | Independiente | 2:1 |  |
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| 4. Round | 21/06/2022 | Newell's Old Boys | - | Argentinos Juniors | 1:0 | |
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| 5. Round | 27/06/2022 | Argentinos Juniors | - | Arsenal de Sarandí | 1:1 | ||||
| 6. Round | 01/07/2022 | Central Córdoba SdE | - | Argentinos Juniors | 1:2 | ||||
| 7. Round | 12/07/2022 | Argentinos Juniors | - | Tigre | 2:1 | ||||
| 8. Round | 16/07/2022 | Barracas Central | - | Argentinos Juniors | 1:3 | |
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| 9. Round | 20/07/2022 | Argentinos Juniors | - | Boca Juniors | 2:0 |
Argentina
Paraguay