| 1. Round | 11/02/2022 | Platense II | - | Talleres de Córdoba II | 1:1 | ||||
| 2. Round | 15/02/2022 | Atlético Tucumán II | - | Platense II | 3:1 | ||||
| 4. Round | 27/02/2022 | Platense II | - | Banfield II | 1:2 | ||||
| 5. Round | 28/03/2022 | Unión de Santa Fe II | - | Platense II | 0:4 | ||||
| 12. Round | 25/04/2022 | Defensa y Justicia II | - | Platense II | 1:1 | ||||
| 13. Round | 02/05/2022 | Platense II | - | Argentinos Juniors II | 1:1 | ||||
| 14. Round | 05/05/2022 | River Plate II | - | Platense II | 2:2 |
Argentina