| 1. Round | 13/02/2022 | Gimnasia de Mendoza | - | San Martín de San Juan | 0:1 | ||||
| 2. Round | 19/02/2022 | San Martín de San Juan | - | All Boys | 0:1 |  |
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| 3. Round | 27/02/2022 | Güemes de SdE | - | San Martín de San Juan | 1:1 | ||||
| 4. Round | 06/03/2022 | San Martín de San Juan | - | Deportivo Riestra | 0:1 | |
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| 5. Round | 11/03/2022 | Belgrano de Córdoba | - | San Martín de San Juan | 2:0 | ||||
| 6. Round | 18/03/2022 | San Martín de San Juan | - | Villa Dálmine | 4:0 | ||||
| 7. Round | 22/03/2022 | Almirante Brown | - | San Martín de San Juan | 1:0 | ||||
| 16. Round | 21/05/2022 | San Martín de San Juan | - | Nueva Chicago | 3:1 | ||||
| 30. Round | 20/08/2022 | San Martín de San Juan | - | Guillermo Brown | 4:1 |
Argentina