| 6. Round | 10/03/2022 | River Plate II | - | Gimnasia de La Plata II | 2:4 | ||||
| 7. Round | 18/03/2022 | River Plate II | - | Boca Juniors II | 0:0 | ||||
| 8. Round | 01/04/2022 | Defensa y Justicia II | - | River Plate II | 2:0 |  |
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| 11. Round | 20/04/2022 | Talleres de Córdoba II | - | River Plate II | 1:1 | ||||
| 12. Round | 25/04/2022 | River Plate II | - | Atlético Tucumán II | 4:0 |
Argentina