| 1. Round | 09/01/2017 | Puebla FC | - | CF Monterrey | 2:3 | ||||
| 2. Round | 14/01/2017 | Club Tijuana | - | Puebla FC | 6:2 | ||||
| 3. Round | 23/01/2017 | Puebla FC | - | Gallos Blancos | 0:0 | ||||
| 4. Round | 30/01/2017 | Santos Laguna | - | Puebla FC | 2:0 | ||||
| 5. Round | 04/02/2017 | Puebla FC | - | Atlas Guadalajara | 1:1 | ||||
| 6. Round | 12/02/2017 | CF América | - | Puebla FC | 0:0 | ||||
| 8. Round | 26/02/2017 | Deportivo Toluca | - | Puebla FC | 1:3 | ||||
| 9. Round | 05/03/2017 | Puebla FC | - | UANL Tigres | 0:2 | ||||
| 11. Round | 20/03/2017 | Puebla FC | - | Monarcas Morelia | 0:1 | ||||
| 12. Round | 02/04/2017 | CF Pachuca | - | Puebla FC | 0:0 | ||||
| 14. Round | 17/04/2017 | Puebla FC | - | Cruz Azul | 2:1 |  |
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| 15. Round | 23/04/2017 | Club León | - | Puebla FC | 1:0 | |
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| 16. Round | 01/05/2017 | Puebla FC | - | Club Necaxa | 0:1 | ||||
| 17. Round | 07/05/2017 | Pumas UNAM | - | Puebla FC | 0:1 |
Argentina