| 1. Round | 16/02/2021 | Independiente | - | Lanús | 0:1 | ||||
| 2. Round | 21/02/2021 | Patronato de Paraná | - | Independiente | 0:1 | ||||
| 3. Round | 27/02/2021 | Independiente | - | Gimnasia de La Plata | 1:0 | ||||
| 4. Round | 05/03/2021 | Newell's Old Boys | - | Independiente | 1:2 | ||||
| 7. Round | 29/03/2021 | Independiente | - | Boca Juniors | 1:1 |  |
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| 8. Round | 03/04/2021 | Talleres de Córdoba | - | Independiente | 3:1 | ||||
| 9. Round | 11/04/2021 | Racing Club | - | Independiente | 1:0 | ||||
| 12. Round | 02/05/2021 | Independiente | - | Atlético Tucumán | 0:1 |
Argentina