2. Round | 29/08/2021 | AS Cittadella | - | FC Crotone | 4:2 | ||||
3. Round | 11/09/2021 | FC Crotone | - | Reggina 1914 | 1:1 | ||||
4. Round | 17/09/2021 | Brescia Calcio | - | FC Crotone | 2:2 | ||||
5. Round | 21/09/2021 | FC Crotone | - | US Lecce | 0:3 | ||||
7. Round | 02/10/2021 | FC Crotone | - | Ascoli Calcio | 2:2 | ||||
8. Round | 16/10/2021 | FC Crotone | - | AC Pisa | 2:1 | ||||
9. Round | 22/10/2021 | US Alessandria 1912 | - | FC Crotone | 1:0 | ||||
10. Round | 28/10/2021 | FC Crotone | - | Benevento Calcio | 0:2 | ||||
11. Round | 01/11/2021 | Frosinone Calcio | - | FC Crotone | 2:1 | ||||
12. Round | 07/11/2021 | FC Crotone | - | AC Monza | 1:1 | ||||
13. Round | 20/11/2021 | AC Perugia Calcio | - | FC Crotone | 2:0 | ||||
14. Round | 26/11/2021 | FC Crotone | - | Vicenza Virtus | 0:1 | ||||
15. Round | 29/11/2021 | Ternana Calcio | - | FC Crotone | 1:0 | ||||
18. Round | 18/12/2021 | FC Crotone | - | Pordenone Calcio | 4:1 |