| 1. Round | 11/06/2022 | Cañuelas | - | Villa San Carlos | 0:0 | ||||
| 2. Round | 18/06/2022 | Villa San Carlos | - | Comunicaciones de Buenos Aires | 1:1 |  |
|||
| 3. Round | 26/06/2022 | CA Los Andes | - | Villa San Carlos | 0:3 | ||||
| 4. Round | 03/07/2022 | Villa San Carlos | - | Ituzaingó | 1:2 | ||||
| 5. Round | 11/07/2022 | Fénix | - | Villa San Carlos | 1:1 | ||||
| 7. Round | 23/07/2022 | Armenio | - | Villa San Carlos | 1:1 | |
|||
| 8. Round | 31/07/2022 | Villa San Carlos | - | Dock Sud | 0:1 | ||||
| 9. Round | 06/08/2022 | UAI Urquiza | - | Villa San Carlos | 1:0 | ||||
| 11. Round | 20/08/2022 | Villa San Carlos | - | Defensores Unidos de Zárate | 1:0 | ||||
| 12. Round | 31/08/2022 | Talleres (RdE) | - | Villa San Carlos | 1:2 | ||||
| 13. Round | 04/09/2022 | Villa San Carlos | - | Deportivo Merlo | 1:0 |
Argentina