| 1. Round | 23/08/1980 | AC Bellinzona | - | Servette FC | 0:0 | ||||
| 2. Round | 30/08/1980 | FC Luzern | - | AC Bellinzona | 3:2 | ||||
| 3. Round | 06/09/1980 | AC Bellinzona | - | Grasshopper Club Zürich | 0:2 | ||||
| 4. Round | 13/09/1980 | AC Bellinzona | - | FC Nordstern Basel | 0:2 | ||||
| 5. Round | 20/09/1980 | Lausanne Sports | - | AC Bellinzona | 3:0 | ||||
| 6. Round | 04/10/1980 | AC Bellinzona | - | BSC Young Boys | 0:3 | ||||
| 7. Round | 08/10/1980 | Neuchâtel Xamax FC | - | AC Bellinzona | 3:0 | ||||
| 17. Round | 22/03/1981 | FC Nordstern Basel | - | AC Bellinzona | 1:2 | ||||
| 18. Round | 05/04/1981 | AC Bellinzona | - | Lausanne Sports | 1:2 | ||||
| 19. Round | 11/04/1981 | BSC Young Boys | - | AC Bellinzona | 2:0 | ||||
| 23. Round | 16/05/1981 | FC Chiasso | - | AC Bellinzona | 5:1 | ||||
| 26. Round | 13/06/1981 | FC Sion | - | AC Bellinzona | 3:1 |
Switzerland