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| 16/05/1981 | 16:30 | FC St. Gallen | - | FC Nordstern Basel | 1:0 (0:0) | |
| 17:15 | Neuchâtel Xamax FC | - | Grasshopper Club Zürich | 0:0 (0:0) | ||
| 19:00 | FC Zürich | - | Lausanne Sports | 2:0 (1:0) | ||
| 19:00 | FC Basel | - | FC Luzern | 4:4 (0:1) | ||
| 19:15 | FC Sion | - | Servette FC | 0:3 (0:2) | ||
| 19:30 | FC Chiasso | - | AC Bellinzona | 5:1 (1:0) | ||
| 19:30 | CS Chênois | - | BSC Young Boys | 1:2 (0:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Zürich | 23 | 17 | 2 | 4 | 50:27 | 23 | 36:10 |
| 2 |
|
Grasshopper Club Zürich | 23 | 10 | 11 | 2 | 41:20 | 21 | 31:15 |
| 3 |
|
Neuchâtel Xamax FC | 23 | 12 | 6 | 5 | 39:24 | 15 | 30:16 |
| 4 |
|
BSC Young Boys | 23 | 10 | 9 | 4 | 41:31 | 10 | 29:17 |
| 5 |
|
Lausanne Sports | 23 | 11 | 4 | 8 | 36:27 | 9 | 26:20 |
| 6 |
|
FC Basel | 23 | 9 | 7 | 7 | 44:40 | 4 | 25:21 |
| 7 |
|
Servette FC | 23 | 7 | 9 | 7 | 35:32 | 3 | 23:23 |
| 8 |
|
FC Sion | 23 | 7 | 7 | 9 | 30:35 | -5 | 21:25 |
| 9 |
|
FC Luzern | 23 | 6 | 8 | 9 | 36:40 | -4 | 20:26 |
| 10 |
|
FC St. Gallen | 23 | 7 | 6 | 10 | 33:38 | -5 | 20:26 |
| 11 |
|
FC Chiasso | 23 | 5 | 8 | 10 | 28:40 | -12 | 18:28 |
| 12 |
|
AC Bellinzona | 23 | 6 | 4 | 13 | 22:42 | -20 | 16:30 |
| 13 |
|
FC Nordstern Basel | 23 | 4 | 6 | 13 | 22:36 | -14 | 14:32 |
| 14 |
|
CS Chênois | 23 | 2 | 9 | 12 | 20:45 | -25 | 13:33 |
| Champions League | |
| Europa League | |
| Relegation |
