| 6. Round | 11/09/1999 | Independiente | - | River Plate | 1:1 | ||||
| 7. Round | 16/09/1999 | River Plate | - | Lanús | 3:1 | ||||
| 8. Round | 25/09/1999 | Argentinos Juniors | - | River Plate | 2:0 | ||||
| 10. Round | 09/10/1999 | Gimnasia de Jujuy | - | River Plate | 0:2 | ||||
| 11. Round | 16/10/1999 | River Plate | - | Boca Juniors | 2:0 | ||||
| 12. Round | 30/10/1999 | River Plate | - | Newell's Old Boys | 2:0 | ||||
| 13. Round | 06/11/1999 | Unión de Santa Fe | - | River Plate | 1:2 | ||||
| 14. Round | 13/11/1999 | River Plate | - | Gimnasia de La Plata | 2:0 | ||||
| 15. Round | 20/11/1999 | Talleres de Córdoba | - | River Plate | 1:4 |  |
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| 16. Round | 27/11/1999 | River Plate | - | Racing Club | 1:0 | ||||
| 17. Round | 04/12/1999 | Chacarita Juniors | - | River Plate | 4:4 | ||||
| 18. Round | 11/12/1999 | River Plate | - | Ferro Carril Oeste | 4:1 | ||||
| 19. Round | 18/12/1999 | San Lorenzo | - | River Plate | 2:2 | |
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