| 1. Round | 08/02/2008 | San Lorenzo | - | Newell's Old Boys | 0:2 |  |
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| 2. Round | 17/02/2008 | Newell's Old Boys | - | River Plate | 0:0 | |
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| 4. Round | 02/03/2008 | Newell's Old Boys | - | Racing Club | 1:0 | |
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| 5. Round | 08/03/2008 | Vélez Sarsfield | - | Newell's Old Boys | 1:0 | ||||
| 6. Round | 16/03/2008 | Newell's Old Boys | - | Arsenal de Sarandí | 4:1 | ||||
| 7. Round | 24/03/2008 | Lanús | - | Newell's Old Boys | 1:1 | ||||
| 8. Round | 30/03/2008 | Newell's Old Boys | - | Tigre | 1:1 | ||||
| 9. Round | 05/04/2008 | Rosario Central | - | Newell's Old Boys | 0:1 | ||||
| 15. Round | 16/05/2008 | Colón de Santa Fe | - | Newell's Old Boys | 1:1 | ||||
| 16. Round | 26/05/2008 | Newell's Old Boys | - | Olimpo de Bahía Blanca | 0:1 |  |
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| 18. Round | 07/06/2008 | Newell's Old Boys | - | Gimnasia de Jujuy | 2:2 | ||||
| 19. Round | 21/06/2008 | Newell's Old Boys | - | San Martín de San Juan | 1:0 |
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