| 2. Round | 15/02/2022 | Atlético Tucumán II | - | Platense II | 3:1 |  |
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| 3. Round | 19/02/2022 | Unión de Santa Fe II | - | Atlético Tucumán II | 1:0 | ||||
| 4. Round | 25/02/2022 | Atlético Tucumán II | - | Patronato de Paraná II | 4:1 | |
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| 7. Round | 21/03/2022 | Atlético Tucumán II | - | Central Córdoba SdE II | 2:2 | ||||
| 8. Round | 04/04/2022 | San Lorenzo II | - | Atlético Tucumán II | 1:1 | |
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| 12. Round | 25/04/2022 | River Plate II | - | Atlético Tucumán II | 4:0 | ||||
| 13. Round | 30/04/2022 | Atlético Tucumán II | - | Talleres de Córdoba II | 0:2 |
Argentina
Italy