20. Round | 05/11/2021 | Vélez Sarsfield II | - | San Lorenzo II | 2:0 | ||||
21. Round | 18/11/2021 | San Lorenzo II | - | Gimnasia de La Plata II | 4:1 | ||||
22. Round | 23/11/2021 | Aldosivi II | - | San Lorenzo II | 1:0 | ||||
24. Round | 06/12/2021 | Independiente II | - | San Lorenzo II | 1:0 | ||||
25. Round | 10/12/2021 | San Lorenzo II | - | Newell's Old Boys II | 2:1 |