| 2. Round | 13/02/2016 | Godoy Cruz | - | Independiente | 1:1 | ||||
| 3. Round | 17/02/2016 | Independiente | - | Rosario Central | 0:2 | ||||
| 4. Round | 21/02/2016 | Independiente | - | Racing Club | 1:1 | ||||
| 6. Round | 06/03/2016 | Independiente | - | Colón de Santa Fe | 4:1 | ||||
| 7. Round | 12/03/2016 | Banfield | - | Independiente | 1:3 | ||||
| 8. Round | 19/03/2016 | Independiente | - | Patronato de Paraná | 2:1 | ||||
| 10. Round | 10/04/2016 | Independiente | - | Olimpo de Bahía Blanca | 0:0 | ||||
| 11. Round | 17/04/2016 | Vélez Sarsfield | - | Independiente | 0:2 |  |
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| 12. Round | 24/04/2016 | Racing Club | - | Independiente | 0:0 | ||||
| 13. Round | 30/04/2016 | Independiente | - | San Lorenzo | 0:1 | ||||
| 14. Round | 09/05/2016 | Gimnasia de La Plata | - | Independiente | 3:3 | |
Argentina