1. Round | 17/10/2020 | Sol de América | - | Guaraní | 1:0 | ||||
2. Round | 26/10/2020 | Guaraní | - | Cerro Porteño | 1:1 | ||||
4. Round | 06/11/2020 | Guaraní | - | General Díaz | 2:0 | ||||
5. Round | 12/11/2020 | Club Nacional | - | Guaraní | 0:0 | ||||
6. Round | 16/11/2020 | Guaraní | - | San Lorenzo | 2:1 | ||||
8. Round | 29/11/2020 | Guaraní | - | Sportivo Luqueño | 2:1 | ||||
9. Round | 06/12/2020 | Guaraní | - | Club Olimpia | 2:0 |