2. Round 21/08/2021 Gaziantep FK - Beşiktaş 0:0
3. Round 28/08/2021 Yeni Malatyaspor - Gaziantep FK 2:0
4. Round 13/09/2021 Gaziantep FK - Antalyaspor 2:0 yellow card
5. Round 18/09/2021 Sivasspor - Gaziantep FK 1:1 Goal
6. Round 22/09/2021 Gaziantep FK - İstanbul Başakşehir 1:0
7. Round 25/09/2021 Adana Demirspor - Gaziantep FK 4:0 yellow card
8. Round 03/10/2021 Gaziantep FK - Altay Izmir 4:1
9. Round 18/10/2021 Hatayspor - Gaziantep FK 2:1
10. Round 23/10/2021 Gaziantep FK - Giresunspor 1:1 yellow card
11. Round 31/10/2021 Galatasaray - Gaziantep FK 2:0
12. Round 05/11/2021 Gaziantep FK - Kasımpaşa SK 2:0 Goal yellow card
14. Round 28/11/2021 Gaziantep FK - Konyaspor 3:2 Goal
15. Round 06/12/2021 Göztepe - Gaziantep FK 2:1
16. Round 13/12/2021 Gaziantep FK - Fenerbahçe 3:2 GoalGoal yellow card
17. Round 19/12/2021 Kayserispor - Gaziantep FK 0:0
18. Round 22/12/2021 Gaziantep FK - Alanyaspor 2:1
19. Round 26/12/2021 Çaykur Rizespor - Gaziantep FK 0:1
20. Round 08/01/2022 Gaziantep FK - Fatih Karagümrük 3:1 Goal
22. Round 20/01/2022 Gaziantep FK - Yeni Malatyaspor 0:0 yellow card
23. Round 23/01/2022 Antalyaspor - Gaziantep FK 0:0
24. Round 05/02/2022 Gaziantep FK - Sivasspor 5:1
26. Round 20/02/2022 Gaziantep FK - Adana Demirspor 0:3
27. Round 27/02/2022 Altay Izmir - Gaziantep FK 3:2
28. Round 07/03/2022 Gaziantep FK - Hatayspor 2:2
29. Round 14/03/2022 Giresunspor - Gaziantep FK 2:1
30. Round 20/03/2022 Gaziantep FK - Galatasaray 3:1 Goal
31. Round 03/04/2022 Kasımpaşa SK - Gaziantep FK 2:1
32. Round 09/04/2022 Gaziantep FK - Trabzonspor 0:0 yellow card
33. Round 17/04/2022 Konyaspor - Gaziantep FK 4:1
34. Round 23/04/2022 Gaziantep FK - Göztepe 1:1 Goal
35. Round 29/04/2022 Fenerbahçe - Gaziantep FK 3:2
36. Round 06/05/2022 Gaziantep FK - Kayserispor 1:1
37. Round 15/05/2022 Alanyaspor - Gaziantep FK 3:0
38. Round 20/05/2022 Gaziantep FK - Çaykur Rizespor 2:0