| 8. Round | 22/09/2017 | Royal Antwerp FC | - | KV Kortrijk | 3:0 | ||||
| 9. Round | 30/09/2017 | Waasland-Beveren | - | Royal Antwerp FC | 3:0 | ||||
| 11. Round | 22/10/2017 | Club Brugge KV | - | Royal Antwerp FC | 1:0 | ||||
| 12. Round | 26/10/2017 | Royal Antwerp FC | - | Standard Liège | 0:0 |  |
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| 13. Round | 29/10/2017 | Royal Excel Mouscron | - | Royal Antwerp FC | 2:2 |  |
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| 14. Round | 05/11/2017 | Royal Antwerp FC | - | Sporting Charleroi | 1:3 | |
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| 15. Round | 18/11/2017 | KAS Eupen | - | Royal Antwerp FC | 0:1 | ||||
| 16. Round | 25/11/2017 | Royal Antwerp FC | - | KV Mechelen | 0:0 | ||||
| 18. Round | 09/12/2017 | Royal Antwerp FC | - | Royal Excel Mouscron | 1:0 | ||||
| 19. Round | 17/12/2017 | SV Zulte Waregem | - | Royal Antwerp FC | 1:2 | |
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| 20. Round | 21/12/2017 | Royal Antwerp FC | - | Sporting Lokeren | 1:2 | |
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| 25. Round | 02/02/2018 | Royal Antwerp FC | - | Waasland-Beveren | 1:2 | ||||
| 27. Round | 17/02/2018 | Royal Antwerp FC | - | KV Oostende | 0:0 |
Uruguay