| Group B | 18/10/2020 | Nacional | - | Fénix | 1:0 | ||||
| Group B | 31/10/2020 | Deportivo Maldonado | - | Nacional | 1:2 | ||||
| Group B | 07/11/2020 | Nacional | - | Defensor Sporting | 3:0 |  |
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| Group B | 12/11/2020 | River Plate | - | Nacional | 0:2 | ||||
| Group B | 21/11/2020 | Nacional | - | Danubio | 0:2 |  |
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| Group B | 29/11/2020 | Boston River | - | Nacional | 0:1 | ||||
| Group B | 13/12/2020 | Peñarol | - | Nacional | 3:2 | ||||
| Final | 14/01/2021 | Nacional | - | Montevideo Wanderers | 4:1 pso | |
Uruguay