| 1. Round | 12/02/2021 | Defensa y Justicia II | - | Huracán II | 3:3 | ||||
| 3. Round | 26/02/2021 | Atlético Tucumán II | - | Huracán II | 1:2 | ||||
| 4. Round | 05/03/2021 | San Lorenzo II | - | Huracán II | 2:2 | ||||
| 5. Round | 12/03/2021 | Huracán II | - | Lanús II | 2:0 | ||||
| 6. Round | 19/03/2021 | Patronato de Paraná II | - | Huracán II | 0:0 | ||||
| 7. Round | 29/03/2021 | Huracán II | - | Gimnasia de La Plata II | 3:2 | ||||
| 8. Round | 02/04/2021 | Newell's Old Boys II | - | Huracán II | 3:0 | ||||
| 9. Round | 09/04/2021 | Huracán II | - | Sarmiento de Junín II | 1:1 | ||||
| 10. Round | 16/04/2021 | Vélez Sarsfield II | - | Huracán II | 2:0 | ||||
| 11. Round | 23/04/2021 | Huracán II | - | Boca Juniors II | 1:4 | ||||
| 12. Round | 30/04/2021 | Talleres de Córdoba II | - | Huracán II | 0:1 | ||||
| 13. Round | 07/05/2021 | Huracán II | - | Independiente II | 0:0 |
Argentina