| 3. Round | 15/06/2022 | Independiente II | - | Argentinos Juniors II | 0:3 | ||||
| 4. Round | 19/06/2022 | Estudiantes II | - | Independiente II | 1:1 | ||||
| 5. Round | 26/06/2022 | Independiente II | - | Patronato de Paraná II | 7:1 | ||||
| 9. Round | 19/07/2022 | Independiente II | - | Defensa y Justicia II | 0:0 | ||||
| 10. Round | 23/07/2022 | Atlético Tucumán II | - | Independiente II | 1:2 |  |
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| 11. Round | 31/07/2022 | Independiente II | - | Colón de Santa Fe II | 1:1 | ||||
| 12. Round | 06/08/2022 | River Plate II | - | Independiente II | 2:1 | ||||
| 13. Round | 10/08/2022 | Independiente II | - | Lanús II | 1:2 |  |
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| 25. Round | 13/10/2022 | Barracas Central II | - | Independiente II | 0:1 | ||||
| 27. Round | 21/10/2022 | Independiente II | - | Boca Juniors II | 0:3 |
Argentina