| 1. Round | 04/02/2018 | Everton | - | Deportes Iquique | 2:3 | ||||
| 2. Round | 10/02/2018 | Deportes Iquique | - | Universidad de Chile | 1:2 | ||||
| 5. Round | 04/03/2018 | Deportes Iquique | - | Universidad Católica | 0:1 | ||||
| 6. Round | 18/03/2018 | San Luis | - | Deportes Iquique | 0:0 |  |
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| 7. Round | 01/04/2018 | Deportes Iquique | - | Universidad de Concepción | 1:3 | ||||
| 8. Round | 07/04/2018 | Deportes Temuco | - | Deportes Iquique | 0:4 | ||||
| 13. Round | 12/05/2018 | Colo-Colo | - | Deportes Iquique | 0:0 | ||||
| 15. Round | 26/05/2018 | O'Higgins | - | Deportes Iquique | 2:1 | ||||
| 18. Round | 06/08/2018 | Unión Española | - | Deportes Iquique | 0:0 | ||||
| 19. Round | 12/08/2018 | Curicó Unido | - | Deportes Iquique | 0:0 | |
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| 22. Round | 01/09/2018 | Deportes Iquique | - | O'Higgins | 3:1 | ||||
| 23. Round | 22/09/2018 | Audax Italiano | - | Deportes Iquique | 3:1 | ||||
| 28. Round | 03/11/2018 | Deportes Iquique | - | Huachipato | 2:0 | ||||
| 30. Round | 02/12/2018 | Deportes Iquique | - | Antofagasta | 0:2 |
Chile