| 1. Round | 06/02/2009 | Tigre | - | San Lorenzo | 1:3 | ||||
| 2. Round | 15/02/2009 | San Lorenzo | - | Godoy Cruz | 1:2 | ||||
| 3. Round | 22/02/2009 | Estudiantes | - | San Lorenzo | 2:1 | ||||
| 4. Round | 01/03/2009 | San Lorenzo | - | River Plate | 5:1 |  |
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| 5. Round | 08/03/2009 | Rosario Central | - | San Lorenzo | 3:1 | ||||
| 6. Round | 14/03/2009 | San Lorenzo | - | Banfield | 3:1 | ||||
| 7. Round | 22/03/2009 | Colón de Santa Fe | - | San Lorenzo | 3:0 |  |
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| 10. Round | 19/04/2009 | San Martín de Tucumán | - | San Lorenzo | 3:0 | ||||
| 12. Round | 02/05/2009 | Gimnasia de La Plata | - | San Lorenzo | 1:2 | ||||
| 13. Round | 10/05/2009 | San Lorenzo | - | Boca Juniors | 1:1 |  |
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| 14. Round | 17/05/2009 | Gimnasia de Jujuy | - | San Lorenzo | 0:3 | ||||
| 15. Round | 23/05/2009 | San Lorenzo | - | Newell's Old Boys | 0:2 | ||||
| 16. Round | 31/05/2009 | Lanús | - | San Lorenzo | 2:1 | ||||
| 17. Round | 14/06/2009 | San Lorenzo | - | Huracán | 0:1 | ||||
| 18. Round | 20/06/2009 | Independiente | - | San Lorenzo | 0:1 | |
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| 19. Round | 04/07/2009 | San Lorenzo | - | Argentinos Juniors | 3:0 |
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