| 11. Round | 24/07/2021 | Nacional Potosí | - | Real Tomayapo | 0:0 | ||||
| 12. Round | 01/08/2021 | Real Tomayapo | - | Oriente Petrolero | 0:1 | ||||
| 13. Round | 05/08/2021 | The Strongest | - | Real Tomayapo | 2:0 | ||||
| 14. Round | 08/08/2021 | Real Tomayapo | - | Jorge Wilstermann | 1:2 |  |
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| 15. Round | 14/08/2021 | Atlético Palmaflor | - | Real Tomayapo | 2:0 | ||||
| 16. Round | 17/08/2021 | Always Ready | - | Real Tomayapo | 3:1 | |
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| 17. Round | 22/08/2021 | Real Tomayapo | - | Royal Pari | 1:4 |
Argentina