| 1. Round | 20/08/2015 | Sportivo Luqueño | - | Club Aurora | 5:1 | ||||
| 2. Round | 15/09/2015 | Sportivo Luqueño | - | Deportivo La Guaira | 4:0 |  |
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| Round of 16 | 23/09/2015 | Deportes Tolima | - | Sportivo Luqueño | 1:1 | |
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| Round of 16 | 29/09/2015 | Sportivo Luqueño | - | Deportes Tolima | 1:0 | ||||
| Quarter-finals | 21/10/2015 | Athletico Paranaense | - | Sportivo Luqueño | 1:0 | ||||
| Quarter-finals | 28/10/2015 | Sportivo Luqueño | - | Athletico Paranaense | 2:0 | |
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| Semi-finals | 04/11/2015 | Sportivo Luqueño | - | Santa Fe | 1:1 | ||||
| Semi-finals | 26/11/2015 | Santa Fe | - | Sportivo Luqueño | 0:0 |  |
Paraguay