| 7. Round | 05/08/2022 | Atlas Guadalajara | - | Gallos Blancos | 3:1 |  |
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| 8. Round | 12/08/2022 | Gallos Blancos | - | Atlético San Luis | 1:1 |  |
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| 9. Round | 17/08/2022 | Mazatlán FC | - | Gallos Blancos | 1:1 | ||||
| 10. Round | 20/08/2022 | Gallos Blancos | - | Club Tijuana | 2:0 | ||||
| 16. Round | 24/08/2022 | Gallos Blancos | - | CF América | 0:1 | ||||
| 11. Round | 27/08/2022 | Cruz Azul | - | Gallos Blancos | 2:1 | ||||
| 12. Round | 02/09/2022 | Gallos Blancos | - | Puebla FC | 1:1 | ||||
| 13. Round | 08/09/2022 | Pumas UNAM | - | Gallos Blancos | 4:1 | ||||
| 15. Round | 19/09/2022 | Club León | - | Gallos Blancos | 3:1 | |
Ecuador