| 1. Round | 12/02/2021 | Central Córdoba SdE II | - | Colón de Santa Fe II | 2:0 | ||||
| 2. Round | 19/02/2021 | Atlético Tucumán II | - | Central Córdoba SdE II | 2:0 | ||||
| 3. Round | 26/02/2021 | San Lorenzo II | - | Central Córdoba SdE II | 2:1 | ||||
| 4. Round | 05/03/2021 | Central Córdoba SdE II | - | Banfield II | 1:0 | ||||
| 5. Round | 12/03/2021 | Aldosivi II | - | Central Córdoba SdE II | 8:0 | ||||
| 6. Round | 19/03/2021 | Central Córdoba SdE II | - | Estudiantes II | 0:1 | ||||
| 7. Round | 26/03/2021 | Rosario Central II | - | Central Córdoba SdE II | 3:1 | ||||
| 8. Round | 02/04/2021 | Central Córdoba SdE II | - | Platense II | 1:1 | ||||
| 9. Round | 09/04/2021 | Argentinos Juniors II | - | Central Córdoba SdE II | 3:0 | ||||
| 10. Round | 16/04/2021 | Central Córdoba SdE II | - | River Plate II | 1:2 | ||||
| 11. Round | 23/04/2021 | Godoy Cruz II | - | Central Córdoba SdE II | 1:0 | ||||
| 12. Round | 30/04/2021 | Central Córdoba SdE II | - | Racing Club II | 1:3 |
Argentina