| 1. Round | 09/08/2008 | Rosario Central | - | Estudiantes | 3:2 |  |
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| 2. Round | 17/08/2008 | River Plate | - | Rosario Central | 2:0 | ||||
| 3. Round | 22/08/2008 | Rosario Central | - | Colón de Santa Fe | 0:1 | ||||
| 4. Round | 30/08/2008 | Rosario Central | - | Banfield | 0:0 | ||||
| 5. Round | 13/09/2008 | San Lorenzo | - | Rosario Central | 2:1 | ||||
| 6. Round | 17/09/2008 | Rosario Central | - | Arsenal de Sarandí | 3:0 | ||||
| 8. Round | 27/09/2008 | Rosario Central | - | San Martín de Tucumán | 1:1 | ||||
| 9. Round | 03/10/2008 | Racing Club | - | Rosario Central | 4:1 | ||||
| 10. Round | 19/10/2008 | Rosario Central | - | Gimnasia de La Plata | 0:1 | ||||
| 11. Round | 26/10/2008 | Boca Juniors | - | Rosario Central | 2:1 | ||||
| 12. Round | 29/10/2008 | Rosario Central | - | Gimnasia de Jujuy | 3:0 |  |
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| 13. Round | 02/11/2008 | Newell's Old Boys | - | Rosario Central | 1:0 | ||||
| 14. Round | 07/11/2008 | Rosario Central | - | Lanús | 1:2 | ||||
| 15. Round | 15/11/2008 | Huracán | - | Rosario Central | 0:2 | ||||
| 16. Round | 22/11/2008 | Rosario Central | - | Independiente | 1:2 | ||||
| 18. Round | 07/12/2008 | Rosario Central | - | Tigre | 2:3 |
Argentina