| 1. Round | 10/08/2008 | San Lorenzo | - | Tigre | 0:1 | ||||
| 2. Round | 17/08/2008 | Godoy Cruz | - | San Lorenzo | 1:2 |  |
|||
| 3. Round | 24/08/2008 | San Lorenzo | - | Estudiantes | 3:0 | ||||
| 4. Round | 31/08/2008 | River Plate | - | San Lorenzo | 0:0 | ||||
| 5. Round | 13/09/2008 | San Lorenzo | - | Rosario Central | 2:1 | ||||
| 6. Round | 16/09/2008 | Banfield | - | San Lorenzo | 1:3 | ||||
| 8. Round | 27/09/2008 | San Lorenzo | - | Arsenal de Sarandí | 2:0 | ||||
| 11. Round | 26/10/2008 | Racing Club | - | San Lorenzo | 2:1 | ||||
| 12. Round | 29/10/2008 | San Lorenzo | - | Gimnasia de La Plata | 1:1 | ||||
| 13. Round | 02/11/2008 | Boca Juniors | - | San Lorenzo | 1:0 | ||||
| 16. Round | 22/11/2008 | San Lorenzo | - | Lanús | 1:3 | ||||
| 17. Round | 02/12/2008 | Huracán | - | San Lorenzo | 1:4 | ||||
| 18. Round | 07/12/2008 | San Lorenzo | - | Independiente | 4:1 | ||||
| 19. Round | 14/12/2008 | Argentinos Juniors | - | San Lorenzo | 0:1 |
Argentina
Italy