| 1. Round | 18/07/2021 | UTA Arad | - | Farul Constanța | 0:0 | ||||
| 2. Round | 23/07/2021 | Argeș Pitești | - | UTA Arad | 0:1 |  |
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| 3. Round | 01/08/2021 | UTA Arad | - | FCSB | 1:1 | ||||
| 4. Round | 06/08/2021 | FC Botoşani | - | UTA Arad | 2:1 | |
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| 5. Round | 14/08/2021 | UTA Arad | - | CS Universitatea Craiova | 1:0 | ||||
| 6. Round | 22/08/2021 | UTA Arad | - | FC Voluntari | 2:0 | ||||
| 7. Round | 30/08/2021 | Gaz Metan Mediaş | - | UTA Arad | 0:1 | ||||
| 8. Round | 10/09/2021 | UTA Arad | - | Rapid Bucureşti | 2:2 | ||||
| 9. Round | 19/09/2021 | Sepsi OSK | - | UTA Arad | 0:0 | ||||
| 10. Round | 26/09/2021 | UTA Arad | - | CFR Cluj | 0:1 | ||||
| 12. Round | 17/10/2021 | UTA Arad | - | FC Universitatea Craiova | 1:0 | ||||
| 13. Round | 25/10/2021 | Academica Clinceni | - | UTA Arad | 0:3 | ||||
| 15. Round | 06/11/2021 | CS Mioveni | - | UTA Arad | 0:0 | ||||
| 16. Round | 20/11/2021 | Farul Constanța | - | UTA Arad | 0:0 | ||||
| 18. Round | 05/12/2021 | FCSB | - | UTA Arad | 2:1 | ||||
| 19. Round | 11/12/2021 | UTA Arad | - | FC Botoşani | 0:0 | ||||
| 20. Round | 14/12/2021 | CS Universitatea Craiova | - | UTA Arad | 0:0 | |
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| 21. Round | 17/12/2021 | FC Voluntari | - | UTA Arad | 2:1 |
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