| 1. Round | 19/08/2023 | Fénix | - | Defensor Sporting | 1:1 | ||||
| 2. Round | 25/08/2023 | Defensor Sporting | - | Montevideo Wanderers | 3:0 |  |
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| 4. Round | 07/10/2023 | Peñarol | - | Defensor Sporting | 2:1 | |
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| 5. Round | 13/10/2023 | Defensor Sporting | - | Montevideo City Torque | 2:0 | ||||
| 6. Round | 18/10/2023 | Liverpool | - | Defensor Sporting | 2:0 | |
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| 7. Round | 21/10/2023 | Defensor Sporting | - | Cerro Largo | 2:0 | ||||
| 8. Round | 05/11/2023 | Plaza Colonia | - | Defensor Sporting | 0:2 | ||||
| 9. Round | 11/11/2023 | Defensor Sporting | - | Racing | 3:0 | ||||
| 10. Round | 15/11/2023 | CA Cerro | - | Defensor Sporting | 1:1 | |
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| 11. Round | 20/11/2023 | Defensor Sporting | - | Boston River | 2:0 | ||||
| 12. Round | 25/11/2023 | Deportivo Maldonado | - | Defensor Sporting | 2:1 | ||||
| 13. Round | 30/11/2023 | Defensor Sporting | - | River Plate | 0:1 | ||||
| 14. Round | 04/12/2023 | Nacional | - | Defensor Sporting | 1:0 |
Uruguay