| 1. Round | 06/09/1980 | Real Murcia | - | FC Barcelona | 1:2 | ||||
| 2. Round | 12/09/1980 | UD Salamanca | - | Real Murcia | 0:3 | ||||
| 3. Round | 20/09/1980 | Real Murcia | - | Real Zaragoza | 0:1 | ||||
| 5. Round | 05/10/1980 | Real Murcia | - | Real Valladolid | 0:0 | ||||
| 8. Round | 26/10/1980 | Sevilla FC | - | Real Murcia | 1:0 | ||||
| 20. Round | 17/01/1981 | Real Zaragoza | - | Real Murcia | 1:6 | ||||
| 25. Round | 21/02/1981 | Real Murcia | - | Sevilla FC | 0:0 | ||||
| 26. Round | 28/02/1981 | Real Murcia | - | Atlético Madrid | 0:2 |
Argentina