| 10. Round | 03/09/2021 | Defensa y Justicia II | - | Central Córdoba SdE II | 0:1 | ||||
| 12. Round | 20/09/2021 | Defensa y Justicia II | - | Banfield II | 0:2 | ||||
| 13. Round | 24/09/2021 | San Lorenzo II | - | Defensa y Justicia II | 0:2 | ||||
| 15. Round | 07/10/2021 | Argentinos Juniors II | - | Defensa y Justicia II | 0:0 | ||||
| 17. Round | 18/10/2021 | Patronato de Paraná II | - | Defensa y Justicia II | 2:2 |
Argentina