| 3. Round | 26/01/2021 | Club Tijuana [Women] | - | Atlas Guadalajara [Women] | 0:1 | ||||
| 5. Round | 04/02/2021 | Club Tijuana [Women] | - | Mazatlán FC [Women] | 0:0 | ||||
| 7. Round | 16/02/2021 | Club Tijuana [Women] | - | Puebla FC [Women] | 0:0 | ||||
| 11. Round | 16/03/2021 | Club Tijuana [Women] | - | Santos Laguna [Women] | 0:1 | ||||
| 14. Round | 06/04/2021 | CF Pachuca [Women] | - | Club Tijuana [Women] | 2:1 | ||||
| 16. Round | 22/04/2021 | Gallos Blancos [Women] | - | Club Tijuana [Women] | 2:1 | ||||
| 17. Round | 04/05/2021 | Club Tijuana [Women] | - | Club Necaxa [Women] | 3:0 |
Mexico