| 4. Round | 09/02/2025 | Deportivo Riestra | - | Defensa y Justicia | 1:1 |  |
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| 5. Round | 12/02/2025 | Newell's Old Boys | - | Defensa y Justicia | 0:1 | ||||
| 11. Round | 28/03/2025 | Defensa y Justicia | - | Tigre | 1:2 | ||||
| 12. Round | 07/04/2025 | Argentinos Juniors | - | Defensa y Justicia | 4:1 | |
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| 13. Round | 14/04/2025 | Defensa y Justicia | - | Unión de Santa Fe | 0:0 |
Colombia