| 1. Round | 08/08/2022 | Crystal Palace U21 | - | Brighton & Hove Albion U21 | 3:2 | ||||
| 2. Round | 12/08/2022 | Manchester United U21 | - | Crystal Palace U21 | 1:5 |  |
|||
| 3. Round | 19/08/2022 | Fulham FC U21 | - | Crystal Palace U21 | 2:2 | ||||
| 4. Round | 26/08/2022 | Crystal Palace U21 | - | Wolverhampton Wanderers U21 | 2:1 |  |
|||
| 5. Round | 03/09/2022 | Crystal Palace U21 | - | Tottenham Hotspur U21 | 3:0 | ||||
| 7. Round | 17/09/2022 | Crystal Palace U21 | - | Chelsea FC U21 | 3:3 | ||||
| 8. Round | 01/10/2022 | West Ham United U21 | - | Crystal Palace U21 | 0:1 | ||||
| 9. Round | 09/10/2022 | Crystal Palace U21 | - | Everton FC U21 | 3:4 | |
|||
| 12. Round | 31/10/2022 | Arsenal FC U21 | - | Crystal Palace U21 | 1:1 | ||||
| 13. Round | 04/11/2022 | Crystal Palace U21 | - | Leicester City U21 | 0:0 |
USA