| 1. Round | 11/02/2012 | Estudiantes | - | Newell's Old Boys | 1:1 |  |
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| 2. Round | 18/02/2012 | Newell's Old Boys | - | Argentinos Juniors | 1:0 | |
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| 3. Round | 26/02/2012 | Boca Juniors | - | Newell's Old Boys | 2:0 | ||||
| 4. Round | 02/03/2012 | Newell's Old Boys | - | Belgrano de Córdoba | 0:2 | |
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| 5. Round | 09/03/2012 | Colón de Santa Fe | - | Newell's Old Boys | 0:3 | ||||
| 6. Round | 18/03/2012 | Newell's Old Boys | - | Atlético Rafaela | 1:0 | |
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| 8. Round | 01/04/2012 | Newell's Old Boys | - | Racing Club | 2:0 | |
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| 9. Round | 08/04/2012 | Godoy Cruz | - | Newell's Old Boys | 1:1 | ||||
| 12. Round | 28/04/2012 | Newell's Old Boys | - | All Boys | 1:1 | ||||
| 13. Round | 06/05/2012 | Olimpo de Bahía Blanca | - | Newell's Old Boys | 1:2 | ||||
| 14. Round | 12/05/2012 | Newell's Old Boys | - | Unión de Santa Fe | 3:1 | ||||
| 15. Round | 18/05/2012 | Tigre | - | Newell's Old Boys | 3:1 | ||||
| 16. Round | 27/05/2012 | San Lorenzo | - | Newell's Old Boys | 3:2 | ||||
| 17. Round | 09/06/2012 | Newell's Old Boys | - | Independiente | 2:1 | ||||
| 18. Round | 15/06/2012 | San Martín de San Juan | - | Newell's Old Boys | 2:1 |  |
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