| 1. Round | 07/08/2022 | Liverpool FC U21 | - | Manchester City U21 | 0:3 | ||||
| 2. Round | 14/08/2022 | Manchester City U21 | - | Leicester City U21 | 3:1 | ||||
| 4. Round | 26/08/2022 | Chelsea FC U21 | - | Manchester City U21 | 2:2 | ||||
| 5. Round | 03/09/2022 | Manchester City U21 | - | West Ham United U21 | 4:1 | ||||
| 8. Round | 02/10/2022 | Wolverhampton Wanderers U21 | - | Manchester City U21 | 1:3 | ||||
| 9. Round | 08/10/2022 | Manchester City U21 | - | Blackburn Rovers U21 | 1:3 | ||||
| 11. Round | 22/10/2022 | Manchester City U21 | - | Crystal Palace U21 | 3:3 | ||||
| 12. Round | 29/10/2022 | Everton FC U21 | - | Manchester City U21 | 6:3 | ||||
| 14. Round | 07/01/2023 | Manchester City U21 | - | Arsenal FC U21 | 6:0 | ||||
| 15. Round | 14/01/2023 | Manchester City U21 | - | Brighton & Hove Albion U21 | 2:1 |
Scotland