| 1. Round | 11/04/2021 | Chaco For Ever | - | Sportivo Las Parejas | 3:1 | ||||
| 2. Round | 18/04/2021 | Boca Unidos | - | Chaco For Ever | 1:1 | ||||
| 3. Round | 25/04/2021 | Chaco For Ever | - | Juventud Unida de Gualeguaychú | 5:0 |  |
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| 4. Round | 02/05/2021 | Gimnasia y Tiro de Salta | - | Chaco For Ever | 1:1 | ||||
| 7. Round | 07/06/2021 | Chaco For Ever | - | Defensores de Pronunciamiento | 2:1 | ||||
| 18. Round | 21/08/2021 | Juventud Unida de Gualeguaychú | - | Chaco For Ever | 0:0 | ||||
| 19. Round | 25/08/2021 | Chaco For Ever | - | Gimnasia y Tiro de Salta | 0:1 | ||||
| 20. Round | 29/08/2021 | Sarmiento de Resistencia | - | Chaco For Ever | 1:1 | ||||
| 22. Round | 10/09/2021 | Defensores de Pronunciamiento | - | Chaco For Ever | 0:2 | ||||
| 23. Round | 18/09/2021 | Chaco For Ever | - | Defensores Belgrano (VR) | 0:0 | ||||
| 25. Round | 29/09/2021 | Chaco For Ever | - | Crucero del Norte | 1:0 |  |
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| 26. Round | 03/10/2021 | Central Norte | - | Chaco For Ever | 2:0 | ||||
| 30. Round | 31/10/2021 | Chaco For Ever | - | Douglas Haig | 1:0 |
Argentina