| 5. Round | 12/02/2022 | CF Monterrey [U18] | - | FC Juárez [U18] | 2:1 | ||||
| 6. Round | 18/02/2022 | FC Juárez [U18] | - | Santos Laguna [U18] | 0:1 | ||||
| 8. Round | 01/03/2022 | Puebla FC [U18] | - | FC Juárez [U18] | 1:1 | ||||
| 9. Round | 04/03/2022 | FC Juárez [U18] | - | Club León [U18] | 0:1 | ||||
| 10. Round | 11/03/2022 | FC Juárez [U18] | - | Atlas Guadalajara [U18] | 0:3 | ||||
| 11. Round | 18/03/2022 | Club Tijuana [U18] | - | FC Juárez [U18] | 3:2 | ||||
| 1. Round | 25/03/2022 | FC Juárez [U18] | - | Club Necaxa [U18] | 5:3 | ||||
| 12. Round | 02/04/2022 | FC Juárez [U18] | - | Pumas UNAM [U18] | 1:2 | ||||
| 14. Round | 15/04/2022 | FC Juárez [U18] | - | CF Pachuca [U18] | 2:0 | ||||
| 15. Round | 19/04/2022 | Deportivo Toluca [U18] | - | FC Juárez [U18] | 4:0 | ||||
| 16. Round | 22/04/2022 | FC Juárez [U18] | - | Mazatlán FC [U18] | 2:2 |
Mexico