| 1. Round | 25/01/2025 | San Lorenzo | - | Talleres de Córdoba | 1:0 | ||||
| 2. Round | 29/01/2025 | Gimnasia de La Plata | - | San Lorenzo | 0:2 | ||||
| 3. Round | 02/02/2025 | San Lorenzo | - | River Plate | 0:0 | ||||
| 4. Round | 08/02/2025 | Vélez Sarsfield | - | San Lorenzo | 0:0 | ||||
| 5. Round | 13/02/2025 | San Lorenzo | - | Platense | 2:1 | ||||
| 6. Round | 18/02/2025 | Instituto de Córdoba | - | San Lorenzo | 0:1 | ||||
| 7. Round | 23/02/2025 | Huracán | - | San Lorenzo | 2:0 | ||||
| 8. Round | 03/03/2025 | San Lorenzo | - | Racing Club | 3:2 |  |
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| 9. Round | 08/03/2025 | San Lorenzo | - | Independiente | 1:2 | ||||
| 10. Round | 15/03/2025 | Godoy Cruz | - | San Lorenzo | 0:0 | ||||
| 11. Round | 28/03/2025 | San Lorenzo | - | Lanús | 1:1 | ||||
| 12. Round | 05/04/2025 | San Martín de San Juan | - | San Lorenzo | 0:1 |  |
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| 13. Round | 12/04/2025 | San Lorenzo | - | Atlético Tucumán | 1:0 | ||||
| 14. Round | 20/04/2025 | Deportivo Riestra | - | San Lorenzo | 0:0 | ||||
| 15. Round | 26/04/2025 | San Lorenzo | - | Rosario Central | 0:1 | |
Argentina