| 1. Round | 14/02/2022 | Deportivo Riestra | - | Ramón Santamarina | 2:0 |  |
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| 2. Round | 21/02/2022 | Ramón Santamarina | - | Belgrano de Córdoba | 0:1 | ||||
| 3. Round | 27/02/2022 | Villa Dálmine | - | Ramón Santamarina | 0:3 | |
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| 4. Round | 07/03/2022 | Ramón Santamarina | - | Almirante Brown | 2:2 | ||||
| 5. Round | 13/03/2022 | Gimnasia de Jujuy | - | Ramón Santamarina | 1:0 | ||||
| 6. Round | 19/03/2022 | Ramón Santamarina | - | Flandria | 1:1 |  |
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| 8. Round | 29/03/2022 | Ramón Santamarina | - | Deportivo Morón | 1:2 |
Argentina